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Those whose bowels are loose and healthy, whose bladder is not feverish, and the mouth of whose bladder is not over narrow, pass water easily, and no solid matter forms in their bladder. But feverishness of the bowels must be accompanied by feverishness of the bladder. For when it is abnormally heated its mouth is inflamed. In this condition it does not expel the urine, but concocts and heats it within itself. The finest part is separated off, and the clearest passes out as urine, while the thickest and muddiest part forms solid matter, which, though at first small, grows in course of time. For as it rolls about in the urine it coalesces with whatever solid matter forms, and so it grows and hardens. When the patient makes water, it is forced by the urine to fall against the mouth of the bladder, and staying the flow of the urine causes violent pain. So that boys that suffer from stone rub and pull at their privy parts, under the impression that there lies the cause of their making water.Coray’s emendation would mean, the cause of the stoppage, an attractive alteration. That my account is correct is shown by the fact that sufferers from stone emit urine that is very clear, as the thickest and muddiest part of it remains and solidifies. This in most cases is the cause of stone. Children get stone also from the milk, if it be unhealthy, too hot and bilious. For it heats the bowels and the bladder, so that the urine is heated and affected as I have described. And my opinion is that we should give to young children only very diluted wine, which heats and parches the veins less. Females suffer less from stone. For their urethra is short and broad, so that the urine is easily expelled. Nor do they rub the privy parts as do males, nor handle the urethra. For it opens directly into the privy parts, which is not so with males, nor is their urethra wide. And they drink more than boys do.